Our Platform
The EVAG Platform
Evanti Bio's platform produces extracellular vesicles displaying membrane targets in a biologically relevant lipid environment. Target expression and vesicle formation occur together, reducing the need for inefficient post-production loading or reconstitution.
The Process
How It Works
Transfection
The selected membrane-target construct is introduced into producer cells.
Expression
The target is expressed in the producer-cell membrane.
Vesicle recruitment
The platform promotes recruitment of the target into budding extracellular vesicles.
Budding and collection
Target-bearing vesicles are released for use in antibody-discovery workflows.
Key Differentiators
Why EVAG
Efficient budding
Target expression drives robust formation of antigen-bearing vesicles.
Biological loading
Targets are incorporated while vesicles are being produced.
Native conformation
Targets remain associated with the lipid bilayer throughout production.
Multivalent display
Multiple antigens may be displayed on the same vesicle.
Workflow compatibility
The platform supports immunization, hybridoma, B-cell, and phage-based discovery approaches.
Choi et al., Science Advances, 2023.
Partner on the Platform
We welcome collaborations with pharma and biotech partners to apply the EVAG platform to your target programs.
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